Tabex is an H-cholinomimetic for the treatment of nicotine addiction. The main active ingridient Cytisine belongs to the group of nicotinic blockers, which are known in the clinical practice as respiratory stimulators. Due to the little toxicity of nicotine and mostly because its’ weaker peripheral effect on the circulatory system, Cytisine can be used as a means of quitting smoking as it interacts with the same receptors in the human body that nicotine does.
Large clinical trials in Bulgaria, Germany, Poland and New Zeland confirmed its effectiveness. It is well known that depressive moods and abstinence syndrome are the most difficult to solve mental conditions that accompany any dependency.
Dosage and administration
The drug is administered perorally according to the following schedule:
First 3 days: 1 tablet 6 times daily (every 2 hours) with a parallel reduction of the number of cigarettes smoked. If the result is unsatisfactory, the treatment is discontinued and a new therapy can be resumed after 2-3 months. In case of good effect, the treatment should continue according to the following schedule:
from the 4th to 12th day - 1 tablet every 2,5 hours (5 tablets daily);
from the 13th to 16th day - 1 tablet every 3 hours (4 tablets daily;)
from the 21st to 25th day - 1-2 tablets daily.
Complete discontinuation of smoking must occur by the 5th day of treatment.
The high doses may provoke nausea, vomiting, dizziness, tachycardia and muscle weakness. These effects pass quickly after the dose is decreased. .
The drug should be administered carefully to patients with exacerbated peptic ulcer. After completing the treatment course, the patients should refrain from smoking even one cigarette, in order to obtain a lasting effect. .