Stimol is a tonic drug used to treat asthenia, which may occur as a result of ageing or stress. It stabilizes metabolic processes and provides for liver detoxification. Stimol helps stimulate recovery after surgery and severe illnesses.
Stimol combines medicinal properties of malate and L-citrulline. Citrulline is an α-amino acid which participates in neutralization of ammonia in liver produced as a result of decomposition of nitrogen-containing compounds. Ammonia is then transformed into urea. Circulating citrulline concentration is a biomarker of intestinal functionality.
Malate is an important intermediate in various metabolic pathways including the Krebs cycle. In guard cells, malate concentration plays a crucial role for stomata movement. It also reduces the amount of lactate in the blood.
Citrulline malate is widely used for the treatment of patients suffering from asthenia to mitigate recovery time following physical activity. Moreover, the consistent search by athletes to obtain a competitive advantage has led to the use of it as a potential ergogenic aid.
The drug is rapidly absorbed in the intestine, and is excreted by the kidneys within 5-6 hours.
Formulation and Packaging
Solution for oral administration in sachets of 10 ml.
Active ingredient: citrulline malate 100 mg/1 ml.
Application and Dosage
To be administered orally with meal washed down by half a glass of water. Dosage for adults and ageing patients is 10 ml 3 times a day; dosage for children under 5 years is 10 ml once a day, 5-15 years – 10 ml twice a day. Recommended length of treatment course is 12 days.
To be administered with caution in patients having low-sodium diet as 1 sachet of the drug contains 30 mg of sodium.
Abdominal pains and allergic response.