Selank® is an anxiolytic peptide drug with nootropic properties. By its structure, Selank is based on endogenous tetrapeptide Tuftsin, which plays an important role in immune system. To slow the breakdown of peptide and prolong its effects, the inventors of Selank added a Glyproline to its structure.
The mechanism of anxiolytic action is related to the regulation of norepinephrine, serotonin and enkephalins levels and their metabolism in the brain. It is suggested that another possible mechanism of action is inhibition of enkephalin-degrading enzymes, which increases the activity of endogenous opioid system and explains the mild analgesic effect of Selank.
Numerous clinical trials confirmed the safety of this peptide, which was found to not form a dependence and to be non-toxic even in doses 200-500 times higher than therapeutic ones.
Primary Uses of Selank® :
Dosage and Administration
One bottle of Selank contains 60 drops, each having 75 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Selank should be taken up to 3 times per day.
On-label regimen of Selank is 3 times a day, 2 drops in each nostril, for a period of 14 days.
Irritation of the nasal mucosa and very rare allergic reactions.
Interaction With Other Drugs
Selank has no effect on depressants or stimulants including Haloperidol, Pentobarbital, Hexobarbital and analeptics. It can be combined with psychotherapy. It is safe to use with ethanol containing substances.
Keep in a dark place at a temperature less than 10°C (50°F) for up to two years.
Note: If there is a need to increase the effect of Selank, a second dose should be taken 15-minutes after the first one.