Nootropil [Piracetam]


Piracetam is a GABA derivative and the reference nootropic drug.

The exact mechanism of action of Piracetam is not fully understood. It is suggested that the drug increases the oxygen and glucose consumption in the brain and acts as a positive allosteric modulator of AMPA receptors.

Indications for use are:

  • Symptomatic treatment of organic brain syndrome, such as age-related memory and attention impairments
  • Ischemic stroke
  • Alcohol abstinence syndrome and cognitive impairments caused by chronic alcoholism
  • Traumatic brain injuries
  • Vertigo
  • Adjunctive therapy of learning disabilities in children

Piracetam is also very effective for preventing blood clothing issues, increasing longevity and maintaining mental abilities in older patients. It was also found to improve the communication between two hemispheres of the brain. However, most of studies carried on healthy people note a high inter-individual variability in terms of effects and their extent.

It is recommended to take Piracetam alongside with choline supplementation, as they have a synergistic effect.

Dosage and administration

The dosage for symptomatic treatment of cognitive impairments into 2.4-4.8 grams a day, split in 2-3 doses, taken with a meal or on an empty stomach. To avoid sleep disturbances, do not take Piracetam after 5 PM.

Side effects

  • Nervous system: hyperkinesis, irritability, sleepiness, depression, fatigue, headaches, vertigo, insomnia, agitation, anxiety, tremor, ataxia, complications of epilepsy, hallucinations, delirium, hypersexuality.
  • Digestive system: nausea, diarrhea, abdominal pain.
  • Allergic reactions
  • Hypertension
  • Hypotension
  • Weight gain


  • Hypersensitivity
  • Hemorrhagic stroke
  • Terminal stage of renal insufficiency
  • Pregnancy and lactation
  • Age below 1 years old

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