Piracetam is a GABA derivative and the reference nootropic drug.
The exact mechanism of action of Piracetam is not fully understood. It is suggested that the drug increases the oxygen and glucose consumption in the brain and acts as a positive allosteric modulator of AMPA receptors.
Indications for use are:
Piracetam is also very effective for preventing blood clothing issues, increasing longevity and maintaining mental abilities in older patients. It was also found to improve the communication between two hemispheres of the brain. However, most of studies carried on healthy people note a high inter-individual variability in terms of effects and their extent.
It is recommended to take Piracetam alongside with choline supplementation, as they have a synergistic effect.
Dosage and administration
The dosage for symptomatic treatment of cognitive impairments into 2.4-4.8 grams a day, split in 2-3 doses, taken with a meal or on an empty stomach. To avoid sleep disturbances, do not take Piracetam after 5 PM.