Cordiamine [Nikethamide]


Nikethamide is a stimulant drug with analeptic properties. It is used as a treatment for tranquilizer overdoses and hypotension, back then it was known under the brand name of Coramine.

As of today, Nikethamide is marketed in Russia as a drug for circulatory shock, asphyxia, and tranquilizers poisoning. In Europe, the drug is sold under the brand names of Glucardiamid and Gly-Coramin as Nikethamide+Glucose lozenges and is used to relieve fatigue symptoms.

Nikethamide does potentiate the effects of psychostimulant and antidepressant drugs and decreases the effects of narcotic analgesics, hypnotics, antipsychotics, and anxiolytics.

Professional athletes should note that the drug is banned by world anti-doping agency.

Hanseler AG Gly-Coramin page

Dosage and administration

The dosage is 15-40 drops 2-3 times a day. The maximum single dose is 60 drops; maximum daily dose is 180 drops.

Side effects

  • Anxiety
  • Muscle twitches
  • Hyperaemia
  • Skin itching
  • Nausea
  • Arrhythmia
  • Allergic reactions


  • Hypersensitivity
  • Predisposition to convulsions
  • Epilepsy

The drug may cause seizures if taken in excessive dosage, please do not overdose.