Magne B6 is a drug intended to restore the amount of magnesium in the body. Normal levels of magnesium are important for the maintenance of heart and nervous system function. Pyridoxine (vitamin B6), one of the drug’s main ingredients, participates in various metabolic processes, and in regulating metabolism of the nervous system, in particular.
Low levels of magnesium are the evidence of magnesium deficiency, also known as hypomagnesemia. It may cause fatigue or muscle weakness, mental numbness and lack of emotion. Scientists have suggested that deficiency may also cause anxiety and raise blood pressure.
Magnesium deficiency (might be in combination with other deficiencies) with increased irritability, sleep disorders, stomach cramps, palpitations, fatigue, pain and muscle cramps or tingling sensation.
Coated tablets. Active ingredients: magnesium lactate dihydrate 470 mg (equal to 48 mg of Mg2+, or magnesium ion) and pyridoxine hydrochloride 5 mg.
Dosage and administration
Coated tablets: Daily dose is 6-8 tablets for adults and 4-6 tablets for children from 6 years of age. It is recommended to divide the daily dose into 2-3 administrations. Take the tablets with meals washed down by a glass of water.
Average length of treatment course is one month.
Once the amount of magnesium stabilizes, it is recommended to discontinue treatment.
- acute kidney failure;
- children under 6 years (for tablets) or under 1 year (for solution);
- fructose intolerance;
- glucose or galactose malabsorption;
- sucrase-isomaltase deficiency;
- hypersensitivity to the components of the drug.
It is recommended to use the drug with caution in patients with chronic kidney disease in stages other than acute as it may cause hypermagnesemia.
Co-administration with drugs containing phosphates and calcium salts reduces magnesium absorption from the digestive system.
Magne B6 reduces absorption of tetracycline and iron.
It also lowers the effect of clot-busting drugs.
Pyridoxine inhibits the activity of levodopa.
Abdominal pains, nausea, vomiting, flatulence, constipation or allergic response.
Magnesium overdose does not cause intoxication in patients with normal kidney function. Though it may occur in patients with chronic kidney disease.
The symptoms include low blood pressure, nausea, vomiting, depressive disorder, slowing reflexes, respiratory depression, coma, cardiac arrest, heart paralysis and anuria.
Recommended treatment: rehydration and forced diuresis. In case of chronic kidney disease hemodialysis or peritoneal dialysis may be required.