Ethoxidol is a combination drug that inhibits free radical processes and has antioxidant, membrane-protective, anti-hypoxic, nootropic, anti-convulsant, anxiolytic and stress-protective effect. It contains ethylme-thylhydroxypyridine malate and other active ingredients such as dimethylethanolamine (DMAE), N-Acetyl-DL-glutamic acid and glycine.
Ethoxidol can be used in anti-ischemic therapy as it stimulates blood flow in the penumbra. It also reduces total cholesterol and low-density lipoproteins.
The drug increases resistance towards various damaging factors, as well as pathological conditions such as shock, hypoxia, ischemia, cerebrovascular ac-cidents and intoxication with alcohol and antipsychotics (neuroleptics).
Active ingredients: ethylmethylhydroxypyridine malate 100 mg, N-Acetyl-DL-glutamic acid 68 mg, dimethylethanolamine 32 mg and glycine 20 mg;
Ethoxidol’s effect is driven by its antioxidant, anti-hypoxic and membrane-protective properties. It inhibits lipid peroxidation, increases the lipid-protein ratio, stabilizes the membrane fluidity and stimulates the membrane-bound enzymes and receptors.
After ingestion, the drug is absorbed from the gastrointestinal tract and gets distributed to the organs and tissues of the body. It stays in the blood plasma for 7-10 hours. Then Ethoxidol is extensively metabolized in the liver.
Dosage and application
Oral administration, chewable tablets.
As part of complex therapy of coronary heart disease, the recommended dosage is 1 tablet (100 mg) 3 times a day. The maximum single dose is 200 mg, the maximum daily dose is 800 mg. The minimum recommended treatment course is 2 months.
As part of complex therapy of mild or moderate cognitive impairment, the recommended dosage is 1 tablet (100 mg) 3-4 times a day with no limit to the duration of treatment.
Ethoxidol enhances the effect of anticonvulsant drugs (carbamazepine), antiparkinson medication (levodopa) and benzodiazepine anxiolytics. It also re-duces the toxic effects of ethanol.