Donormyl (Doxylamine succinate) is over-the-counter antihistamine sleeping aid. The sleep-inducing properties of Doxylamine are comparable to that of secobarbital. It is known since 1948.
Donormyl works by inhibiting histamine receptors, thus it is also can be used to alleviate allergy and cold symptoms. Unlike common sleeping pills such as benzodiazepines and benzodiazepine-like drugs, doxylamine is not habit-forming and does not negatively affect sleep quality.
Dosage and administration
The dosage is ½-1 pill a day, 15-30 minutes prior to bedtime. If such dose is ineffective, it can be raised to two pills.
The length of the treatment course is up to 5 days. If you still experience insomnia after the course, you should check with your doctor.
Donormyl does potentiate the depressant effect of sedative antidepressants, barbiturates, benzodiazepines, clonidine, opioids, atipsychotics, anxiolytics, antihistamines, central antihypertensives, thalidomide, baclofen and pizotifen.
Coadministration with muscarinic antagonists increases the risk of adverse effects such as urinary retention, constipations and dry mouth.
Since alcohol does potentiate the sedative effect of most H1 receptor antagonists, you should not take Donormyl with alcohol.