Noopept is a Russian dipeptide nootropic drug. It is one of the most popular nootropics around the world.

It is suggested that Noopept works as a prodrug to cycloprolylglycine. Cycloprolylglycine is an endogenous neuropeptide with anxiolytic and neurotrophic properties and is shown to be a positive allosteric AMPA receptors modulator. The pharmacological effects and uses of Noopept are mostly the same as Piracetam, a reference nootropic drug.

Noopept is used to improve cognitive functions (especially memory) in both healthy and cognitively impaired individuals, and in the therapy of organic brain syndrome.

Its effect is physiological to the human body, as it is based on the formation of active compound cyclopropyl glycine, which is naturally occurring in the brain. Noopept increases alpha/beta1 activity, with 30-min. latency and 40-min. duration in all brain areas. Unlike many other pharmaceuticals, Noopept ® can be officially used both for healthy individuals.

Indications for use are:

  • Traumatic brain injuries
  • Post-concussion syndrome
  • Cerebrovascular disorders
  • Asthenic conditions (aka chronic fatigue)
  • Decreased mental capacity

Noopept does have cumulative action, thus it is advised to take it for at least couple weeks to experience therapeutic effects. A choline-rich diet or additional supplementation with Choline is recommended while taking Noopept.

Dosage and administration

The recommended dosage is 10mg twice daily after a meal. If necessary, the dosage can be raised to 10mg three times a day. It is not recommended to take Noopept before bed to avoid sleep disturbances. The length of the treatment course is 1.5-3 months. The course can be repeated in 1 month if necessary.

Side effects

  • Allergic reactions
  • Hypertension


  • Hypersensitivity
  • Pregnancy and lactation
  • Lactose intolerance
  • Liver and renal insufficiency


These reviews have been taken from the Russian website

★★★★★ (5/5)

I’m getting old and my brain is getting rusty. After searching the internet I found that the drug Noopept is just what I need, that it will help me to think faster. Bought it, took it for a month, and indeed I started to notice positive improvements.

My drowsiness has gone, brain now works better with the new information, my reaction improved. I even signed for additional educational courses, and surprisingly, I perform same as the people twice younger than me. Memorizing gets easier, but most important that memorized information stay in your memory rather than gets forgotten on the next day.


★★☆☆☆ (2/5)

The neurologist prescribed me two months course of those pills to fix my low well-being caused by poor blood circulation in the brain.

The first impression was good. The first two weeks I felt more energy, everything was easier. Now I think that it was caused by high expectations and placebo effect. After a month I stopped taking it.

I continued the course later and decided to take it for two months as the doctor prescribed. Just from the first days, it solved one of my problems – waking up in the morning. I didn’t have such problems before, even if I slept for 3-5 hours. But maybe because of the stress or because of my age, I’ve needed about 30-40 minutes to wake up. The alarm clock rings every 5 minutes but I can’t even open my eyes. And even after I woke up, I still feel drowsy for about hour. It’s not normal for me, the presence of problems is obvious.

So, after Noopept I started to wake up without problems almost immediately. Regarding the drowsiness and absent-mindedness, I also noticed an improvement. After the three weeks, I realized that this is not a placebo effect, but the actual effects from the drug. And because of this, I admit that it’s working.

Noopept has cumulative action. And after a week I started to notice that I wake up before the alarm. To be exact, my brain is waking up, through my sleep I feel that it’s the morning already and soon I’ll need to wake up. But my body is still inert, I can’t pull myself up, move, or stand up. The next is worse – day to day my brain started to wake up earlier and earlier. My alarm clock is set to 6 AM, I started to wake up at 5 AM, then 4:30 AM, after that at 3:30 AM. And it could be ok if I could really wake up. But at this time my head was full of thought, sometimes I was falling into sleep again and saw weird unpleasant dreams. But I wasn’t able to wake up, can’t even move. So it was just a wasted time. And afternoon I experienced intense drowsiness and sleepines. Fell asleep at my work.

So, how should I interpret this? Pills gave me so much energy, so my need for sleep decreased drastically? Then I would be able to wake up and do something. But laying in the bed while you understand everything but can’t get up is really unpleasant. I tried to fix this, started to take pills at the first half of the day. But it didn’t help.

Besides that, when taking Noopept I experienced increased heart rate in the first half of the day. Of course, I didn’t experience any memory and attention increase on the background of those side effects, everything was exact the opposite. I was exhausted and irritated. So far I took it for seven weeks and then stopped. After cessation side effects disappeared. I guess I am hypersensitive to this drug.


★★★★★ (5/5)

After retirement, I didn’t leave my job because I still feel the desire to work. But the age manifests itself, my brain started to work worse and my memory has weakened. Everything started with my memory, I started to forgot little things, like a shopping list or I might forget my wallet or ID. But my memory was very good before.

Then I noticed that I have problems understanding what I just read/heard. Clearly the signs of the old age. I went to a doctor and he prescribed Noopept for me, I bought it and started a seven weeks course. After finishing the course here is my impression.

The main thing is that my memory has returned. It became almost the same as before, my forgetfulness stopped. While reading the books I noticed that I don’t need to read one sentence many times. And while watching films, no need to rewind it anymore to understand the plot. At my work, sometimes I even perform better than my younger colleagues.


★★★★★ (5/5)

Recently I noticed absent-mindedness that I didn’t experience before. I regularly forgot keys, phone calls or I could forget at grocery what I need to buy. Despite the fact that I was able to memorize everything before without any shopping lists. Summing this up, I experienced some problems with memory. They weren’t significant, but I worried about it and decided to help my brain. After consulting with my nurse friend I bought Noopept and started to take two pills daily.

The 1.5 months course passed. At first, I thought that the drug does not work since I didn’t notice anything. But after some time I’ve changed my mind. Here are the effects I noticed after taking it:

  • More energy in the morning.
  • I’m no longer forgetful.

Didn’t experience any side effects like headaches or allergic reactions, the drug suits me well. I’m thinking about another course in 6-12 months.


★★★☆☆ (3/5)

I take this medication for three weeks, one pill in the morning. And now I have problems falling asleep for the past couple days. It takes an hour or more. Now after reading all the reviews I understood, that this reacting might be caused by the drug, usual reaction. Now I’m stopping taking it. Regarding memory – it became better.


★★★☆☆ (3/5)

Noticed some problems with memory, and my doctor prescribed Noopept for me. Almost finished the pack, only 11 pills left. Theoretically, I already should notice improvements in memory. But sadly, I don’t see any improvements. And I started to sleep poorly (but I don’t know is this caused by this drug or not). According to reviews, it’s a good drug, but I guess it just doesn’t suit me. And because of that, I won’t recommend it.