Metformin is a first-line medication for the treatment of type 2 diabetes. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain.
Metformin is a biguanide antihyperglycemic agent. It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues
Today, metformin has garnered a new reputation as a possible anti-aging pill that influences a host of metabolic and cellular processes closely associated with the development of age-related conditions.
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Adults: The initial dose is 500 mg or 850 mg 2-3 times a day after or during meals. To reduce side effects from the gastrointestinal tract, the daily dose should be divided into 2-3 doses.
The maximum dose is 3000 mg per day, divided into three doses.
Combination with insulin: To achieve better blood glucose control, metformin and insulin can be used as a combination therapy. The usual dose is one tablet 2-3 times a day. The dose of insulin is selected based on the concentration of glucose in the blood.
Children: in children over 10 years old, Metformin can be used both in monotherapy and in combination with insulin. The usual starting dose is 500 mg or 850 mg 1 time per day after or during meals.
The maximum daily dose is 2000 mg, divided into 2-3 doses.
Elderly patients: due to a possible decrease in renal function, the dose of metformin must be selected under regular monitoring of renal function indicators.
The duration of treatment is determined by the doctor.
With caution: Use in people over 60 years who perform heavy physical work, which is associated with an increased risk of developing lactic acidosis; lactation.